How It Works
Bottom Line: This product has no objectively documented value.
714X is a chemical mixture that was developed by Gaston Naessens, a French biologist living in Canada. Although Naessens makes large claims for 714X, including that it can cause cancer regression and revitalize the immune system, the U.S. Food and Drug Administration (F.D.A.) has analyzed the contents of 714X and has found that it contains relatively inactive ingredients: 94% water, 5% nitrate, and tiny amounts of sodium, chloride, and camphor. While such a mixture may not be harmful to the body, there is no reason to believe, nor are there laboratory experiments to show, that 714X could treat cancer, HIV, or any of the other claims. The F.D.A. has voiced concern that patients who use 714X may not seek proper medical treatment, which may be hazardous to their health.
Purported Uses
- To prevent and treat cancer
No scientific evidence supports this use.
- To treat chronic fatigue syndrome
No scientific evidence supports this use.
- To treat HIV and AIDS
No scientific evidence supports this use.
- To relieve muscle pain
No scientific evidence supports this use.
- To treat rheumatoid arthritis
No scientific evidence supports this use.
- To treat systemic lupus erythematosus (SLE)
No scientific evidence supports this use.
Research Evidence
In addition to the lack of laboratory data to support the use of 714X, no clinical trials have studied the effectiveness of 714X against cancer, HIV, or any other claimed use. At the moment there is no evidence for the use of 714X.
Warnings
- 714X is not legal in the United States. The F.D.A. has prosecuted Americans caught selling this product.
- This product is regulated by the FDA as a dietary supplement. Unlike approved drugs, supplements are not required to be manufactured under specific standardized conditions. This product may not contain the labeled amount or may be contaminated. In addition, it may not have been tested for safety or effectiveness.
Side Effects
When 714X is injected, injection site reactions such as redness, swelling, and soreness are often reported.
Special Point
The manufacturer of 714X, Cerbe, Inc., warns that combining 714X with vitamin B12, vitamin E, shark cartilage or bovine cartilage may reduce its effectiveness.
Scientific Name
Trimethylaminohydroxybicycloheptane chloride
Common Name
714X
Clinical Summary
Proprietary product developed and manufactured by Cerbe Inc., Canada. This product has no objectively documented value. Patients use this product to prevent and treat cancer or HIV/AIDS, lupus, fibromyalgia, and chronic fatigue syndrome. 714X is promoted as a sterile, isotonic formulation that contains nitrates (~5%), ammonium (~1.4%), and camphor (0.01%)
(2). 714X is not legal in the United States
(1) and is available only in Canada under the Compassionate Use Program
(3). 714X is injected intralymphatically in the groin area daily for 21 days followed by 3 days off treatment. This cycle is repeated a minimum of three times. Inhalation therapy is used concomitantly for patients with head and neck or lung cancer. Injection site reactions, including redness and soreness, may occur
(2) (3). No published data evaluate 714X for any proposed claim.
Purported uses
Cancer prevention
Cancer treatment
Chronic fatigue syndrome
HIV and AIDS
Muscle pain
Rheumatoid arthritis
Systemic lupus erythematosus (SLE)
Constituents
Water (94%)
Camphor (~<0.01%)
Nitrate (~5%)
Ammonium (~1.4%)
Sodium chloride (~1%)
Ethanol (~1%)
Trace elements (insignificant amounts)
(1)
Mechanism of Action
Developed by Gaston Naessens, 714X is said to produce disease regression, revitalize the immune system, and support host defense mechanisms. Promoters claim that the camphor has selective affinity for cancer cells, while the nitrate component fulfills cancer cells' nitrogen requirement, thereby protecting immune cells. The nitrogen-enriched camphor supposedly antagonizes the secretion of co-cancerogenic K factor (CKF) by cancer cells
(2) (3). No data in the literature support the proposed mechanisms of action or benefits claimed by the manufacturer.
Warnings
714X is not legal in the United States
(1).
Adverse Reactions
Common: Injection site reactions, such as redness, inflammation, and soreness
(2)
Herb-Drug Interactions
Cerbe, Inc. states that decreased efficacy of 714X may occur if administered concurrently with vitamin B12, vitamin E, and shark or bovine cartilage.
(2)
Literature Summary and Critique
No published clinical trials, case reports, or in vitro data support the use of 714X for any proposed claims. Anecdotal reports of animal studies suggest that 714X produces few side effects and is generally well tolerated, but no efficacy data have been reported.
References